Tag: laboratory

TAVI anaesthetics

A Klein (Cambridge, UK) explains the role of an anaesthetist in the transcatheter aortic valve implantation team.

Posted in Aortic valve Tagged with: , , , , , ,

Cardiac Stem Progenitor Cells

G. Ellison (Liverpool & London, UK) discusses cardiac stem cells and myocyte regeneration.

Posted in Heart failure Tagged with: , , , , ,

Red cell washing

N Patel (Bristol, UK) reports on a study of red cell washing in a porcine model , attempting to reduce the incidence of transfusion related acute lung injury.

Posted in Blood Tagged with: , , , , , ,

Blood transfusion audit

S Allard (London, UK) presents a national comparative audit of blood transfusion in cardiac surgery.

Posted in Blood Tagged with: , , , , ,

Off pump CABG should be abandoned

J Sabik (Cleveland, USA), as part of a debate, argues that off-pump CABG should be abandoned as our default procedure. He reviews results from the major trials as well as metaanalyses to support his view.

Posted in Coronary Tagged with: , , , , , , ,

Non RBC components & bleeding

W Lester (Birmingham) considers the use of non-red blood cell components in major haemorrhage, with emphasis on the role of fibrinogen.

Posted in Blood Tagged with: , , , , ,

Bleeding & Factor VII

R Gill (Southampton, UK) considers haemostatic mechanisms and the use of rFVIIa as a bail out adjunct.

Posted in Blood Tagged with: , , , , ,

Emerging blood products

N Currie (London, UK) discusses the emerging roles of fibrinogen concentrate and prothrombin complex concentrate (PCC).

Posted in Blood Tagged with: , , , , , , ,

Coagulopathy diagnosis

K Görlinger (Essen, Germany) gives an overview on the management of postoperative coagulopathy based on ROTEM results.

Posted in Blood, Videos Tagged with: , , , , , ,

Coagulopathy pathogenesis

J Thachil (Manchester, UK) gives some new insights into the coagulation cascade and the pathogenisis of bleeding after cardiac surgery.

Posted in Blood, Videos Tagged with: , , , , ,

Preoperative anaemia management

C von Heymann (Berlin, Germany) reviews the incidence of preoperative anaemia in cardiac surgery and considers its contribution to adverse outcomes.

Posted in Blood, Videos Tagged with: , , , , ,

REPLACE trial of iv fibrinogen

R Gill (Southampton, UK) discusses the role of fibrinogen in coagulation and the REPLACE trial of its use in complex cardiovascular surgery.

Posted in Blood, Videos Tagged with: , , , , , ,

Coagulopathy prevention

D Mazer (Toronto, Canada) discusses the pharmacological prevention of coagulopathy, looking in detail at the evidence for and against the use of tranexamic acid and aprotinin.

Posted in Blood, Videos Tagged with: , , , , , ,

Non red cell treatment and adjuncts

D Mazer (Toronto, Canada) considers the management of postoperative bleeding, looking in particular at the emerging evidence for component therapy.

Posted in Blood, Videos Tagged with: , , , ,

Preoperative anaemia and adverse outcomes

M Ranucci (Milan, Italy) explores the literature evidence for adverse outcomes associated with preoperative anaemia in cardiac surgery.

Posted in Blood Tagged with: , , , , ,

Bleeding & point of care testing

M Ranucci (Milan, Italy) discusses the bleeding patient and point of care testing, particularly with the use of TEG / ROTEM.

Posted in Blood Tagged with: , , , , ,

Tranexamic acid

A Kelleher (London, UK) considers the use of tranexamic acid to reduce bleeding in cardiac surgery.

Posted in Blood Tagged with: , , , ,

Coagulopathy pathogenesis

H New (London, UK) reviews coagulation, tests for coagulopathy, and changes in DIC and acute traumatic coagulopathy. Management strategies are discussed.

Posted in Blood Tagged with: , , , , ,

Blood conservation methods

A Klein (Cambridge, UK) looks at blood conservation measures in cardiac surgery.

Posted in Blood Tagged with: , , , ,

Blood transfusion and adverse outcomes

G Murphy (Leicester, UK) dissects the evidence for an association between blood transfusion and adverse outcome.

Posted in Blood Tagged with: , , , , ,

Blood management

G Murphy (Leicester UK) introduces blood management and how it affects outcomes in cardiac surgery.

Posted in Blood Tagged with: , , , ,

Aprotinin

D Cheng (London, Canada) reviews the rise and fall of aprotinin as an anti-fibrinolytic agent in cardiac surgery.

Posted in Blood Tagged with: , , , , ,

Preoperative anaemia & poor outcomes

A Carey (Plymouth, UK) looks at the impact of low preoperative haemoglobin on outcomes in patients undergoing urgent coronary bypass surgery.

Posted in Blood Tagged with: , , , , , ,

Managing multimodality anti-platelet therapy

W Lester (Birmingham, UK) explains how anti-platelet agents work and gives evidence-based advice on peri-operative management.

Posted in Blood Tagged with: , , , ,

Blood economics

A Hofmann (Perth, Australia) discusses the economics of blood transfusion.

Posted in Blood Tagged with: , , , ,

Haemovigilance

P Bolton – Maggs (Manchester, UK), its Medical Director, reviews the history and role of Serious Hazards of Transfusion (SHOT).

Posted in Blood Tagged with: , , , , ,

Paediatric surgery bleeding

H New (London, UK) presents highlights from a multicentre survey of blood component use in paediatric cardiac surgery.

Posted in Blood, Congenital Tagged with: , , , ,