Tag: blood

Coagulopathy diagnosis

K Görlinger (Essen, Germany) gives an overview on the management of postoperative coagulopathy based on ROTEM results.

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Coagulopathy pathogenesis

J Thachil (Manchester, UK) gives some new insights into the coagulation cascade and the pathogenisis of bleeding after cardiac surgery.

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Intravenous iron for anaemia

T Richards (London, UK) details the importance of iron and its transport mechanisms. He then reviews the history of intravenous iron administration and looks at novel options.

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Anaemia pathogenesis

A Klein (Cambridge, UK) reviews the incidence and causes of anaemia.

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Preoperative anaemia management

C von Heymann (Berlin, Germany) reviews the incidence of preoperative anaemia in cardiac surgery and considers its contribution to adverse outcomes.

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REPLACE trial of iv fibrinogen

R Gill (Southampton, UK) discusses the role of fibrinogen in coagulation and the REPLACE trial of its use in complex cardiovascular surgery.

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Coagulopathy prevention

D Mazer (Toronto, Canada) discusses the pharmacological prevention of coagulopathy, looking in detail at the evidence for and against the use of tranexamic acid and aprotinin.

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Non red cell treatment and adjuncts

D Mazer (Toronto, Canada) considers the management of postoperative bleeding, looking in particular at the emerging evidence for component therapy.

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Bleeding prediction

A Jeppsson (Goteborg, Sweden) assesses how postoperative bleeding might be predicted and thereby prevented.

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Blood economics

A Hofmann (Perth, Australia) discusses the economics of blood transfusion.

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Haemovigilance

P Bolton – Maggs (Manchester, UK), its Medical Director, reviews the history and role of Serious Hazards of Transfusion (SHOT).

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Paediatric surgery bleeding

H New (London, UK) presents highlights from a multicentre survey of blood component use in paediatric cardiac surgery.

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Aprotinin regulation

D Royston (London, UK) reviews the history of aprotinin and its licencing.

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Bleeding assessment

M Besser (Cambridge, UK) discusses assessment of the bleeding patient, looking at laboratory and point of care testing, and considering possible interventions.

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Blood conservation

G Murphy (Leicester, UK) gives an overview of blood management strategies in cardiac surgery.

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Red cell washing

N Patel (Bristol, UK) reports on a study of red cell washing in a porcine model , attempting to reduce the incidence of transfusion related acute lung injury.

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Blood transfusion audit

S Allard (London, UK) presents a national comparative audit of blood transfusion in cardiac surgery.

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Non RBC components & bleeding

W Lester (Birmingham) considers the use of non-red blood cell components in major haemorrhage, with emphasis on the role of fibrinogen.

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Bleeding & Factor VII

R Gill (Southampton, UK) considers haemostatic mechanisms and the use of rFVIIa as a bail out adjunct.

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Emerging blood products

N Currie (London, UK) discusses the emerging roles of fibrinogen concentrate and prothrombin complex concentrate (PCC).

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Preoperative anaemia and adverse outcomes

M Ranucci (Milan, Italy) explores the literature evidence for adverse outcomes associated with preoperative anaemia in cardiac surgery.

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Bleeding & point of care testing

M Ranucci (Milan, Italy) discusses the bleeding patient and point of care testing, particularly with the use of TEG / ROTEM.

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Coagulopathy pathogenesis

H New (London, UK) reviews coagulation, tests for coagulopathy, and changes in DIC and acute traumatic coagulopathy. Management strategies are discussed.

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Blood conservation methods

A Klein (Cambridge, UK) looks at blood conservation measures in cardiac surgery.

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Blood transfusion and adverse outcomes

G Murphy (Leicester, UK) dissects the evidence for an association between blood transfusion and adverse outcome.

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Blood management

G Murphy (Leicester UK) introduces blood management and how it affects outcomes in cardiac surgery.

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Aprotinin

D Cheng (London, Canada) reviews the rise and fall of aprotinin as an anti-fibrinolytic agent in cardiac surgery.

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Preoperative anaemia & poor outcomes

A Carey (Plymouth, UK) looks at the impact of low preoperative haemoglobin on outcomes in patients undergoing urgent coronary bypass surgery.

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